Here is the latest Mid-America sports news from The Associated Press

AMES, Iowa (AP) — Freshman Spencer Sanders threw for 249 yards and two TDs and Oklahoma State upset 23rd-ranked Iowa State 34-27, snapping the Cyclones’ three-game winning streak. Chuba Hubbard had 116 yards rushing for the Cowboys, who used four big plays to snap their two-game skid. Malcolm Rodriguez gave Oklahoma State a 34-27 lead with 6:47 to go on an interception he returned 26 yards for a touchdown.

EVANSTON, Ill. (AP) — Nate Stanley passed for 179 yards and a touchdown and Iowa allowed just 202 yards as the 20th-ranked Hawkeyes routed Northwestern 20-0. Mekhi Sargent had a rushing touchdown and Tyler Goodson added 58 yards rushing on 11 carries as Iowa earned its second shutout of the season. Aidan Smith completed 18 of 32 passes for 138 yards with an interception as Northwestern dropped its fifth straight.

LINCOLN, Neb. (AP) — Peyton Ramsey passed for a career-high 351 yards and two touchdowns, Whop Philyor caught 14 balls for 178 yards, and Indiana became bowl eligible with a 38-31 win over Nebraska. The Hoosiers won a third straight conference game in the same season for the first time since 1993 and won in Lincoln for the first time since 1959.

LINCOLN, Neb. (AP) — Nebraska backup Noah Vedral was injured in the second quarter against Indiana and third-string quarterback Luke McCaffrey has replaced him. Vedral drew the start in place of Adrian Martinez, who injured his left leg in the Oct. 5 game against Northwestern and missed the Cornhuskers’ Oct. 12 game at Minnesota.

MANHATTAN, Kan. (AP) — Kansas State dealt a big blow to No. 5 Oklahoma’s national title hopes, holding on for a 48-41 victory Saturday. Skylar Thompson threw for 213 yards while running for four scores, and the Wildcats’ defense did just enough against Jalen Hurts and the Sooners’ prolific offense. When a video review overturned a final onside kick with 1:45 left, the Wildcats had their first home win over Oklahoma since 1996.

LEXINGTON, Ky. (AP) — Lynn Bowden Jr. rushed for 204 yards and two touchdowns to lead Kentucky to a 29-7 win over Missouri. The two teams combined for seven fumbles and four lost miscues in a steady rain that didn’t seem to bother Bowden, who was nearly unstoppable. Sparked by Bowden, the Wildcats rushed for 297 yards.

LAWRENCE, Kan. (AP) — Douglas Coleman fumbled on a blocked field goal return with two seconds to go and Liam Jones capitalized with a 32-yard field goal to give Kansas a 37-34 win over Texas Tech. Nick McCann blocked Jones’ 40-yard attempt and the ball landed in the hands of Coleman, who ran to his left before attempting a lateral that did not touch another Tech player.

AMES, Iowa (AP) — Freshman Spencer Sanders threw for 249 yards and two TDs and Oklahoma State upset 23rd-ranked Iowa State 34-27 on Saturday, snapping the Cyclones’ three-game winning streak. Chuba Hubbard had 116 yards rushing for the Cowboys (5-3, 2-3 Big 12), who used four big plays to snap their two-game skid.

Malcolm Rodriguez gave Oklahoma State a 34-27 lead with 6:47 to go on an interception he returned 26 yards for a touchdown. Iowa State then stuffed Hubbard on a 4th-and-1 near midfield with just under 3 minutes left. But quarterback Brock Purdy threw another ill-advised pass that was picked off shortly thereafter — then another interception in the final seconds sealed the Cyclones’ fate.

Oklahoma State jumped ahead 21-13 at halftime behind a 71-yard catch and run touchdown from Tylan Wallace, a 50-yard touchdown pass from Sanders to Braydon Johnson and a 65-yard scoring run from Hubbard. Iowa State’s defense stiffened in the second half, and touchdown runs of 9 and 4 yards by freshman Breece Hall pulled the Cyclones even at 27-all with 9:06 left.

But Purdy, whose brilliant play has been a major reason why Iowa State has been so strong since he took over last season, threw a pair of crushing interceptions to fall to 9-3 against Big 12 opponents. He finished 39 of 62 passing for 382 yards.
THE TAKEAWAY
Iowa State: The longest play the Cyclones had allowed entering the day was 46 yards, so the breakdowns were quite uncharacteristic of one of the Big 12’s best defenses. The league remains wide open, especially after Oklahoma lost to Kansas State, but Iowa State squandered a golden opportunity. It’s not all on Purdy though, as Iowa State ran the ball just 25 times in 88 plays.
Oklahoma State: After turning it over eight times in the past two weeks, Sanders took much better care of the ball — though his third-quarter interception set up Hall’s first touchdown run, which cut the Pokes’ lead to 21-20. Still, Oklahoma State is just one win away from bowl eligibility with at least three winnable games to go.
POLL IMPLICATIONS
This loss should knock Iowa State out of the Top 25.
UP NEXT
Iowa State has next week off. The Cyclones play at Oklahoma on Nov. 9.
Oklahoma State hosts TCU on Saturday.

SPRINGFIELD, Mo. (AP) — Will McElvain threw for two touchdowns and ran for another as Northern Iowa scored 29-unanswered points on its way to a 29-6 win over Missouri State on Saturday. McElvain had 238 yards passing for the Panthers (5-3, 3-1 Missouri Valley Football Conference). Isaiah Weston had 157 yards and two touchdowns receiving. Matthew Cook kicked three field goals.

Cook booted a pair of field goals in the second quarter, from 49 and 22 yards, to give Northern Iowa a 6-0 lead. Later, Austin Evans recovered a Missouri State (1-6, 1-3) fumble six yards shy of the Bears end zone, leading to McElvain’s touchdown run two plays later. McElvain followed that with a 46-yard scoring throw to Weston for a 19-0 lead at halftime.

Cook’s 38-yard field goal and McElvain’s 70-yard touchdown pass to Weston late in the third quarter stretched it to 29-0 before the Bears finally scored on a 17-yard touchdown throw from Peyton Huslig to Antwan Woods. Huslig had 153 yards passing for Missouri State.

DES MOINES, Iowa (AP) — Drew Lauer rushed 28 times for a career-high 242 yards and Drake stayed undefeated in the Pioneer League with a 36-17 win over Morehead State on Saturday. The Bulldogs (4-3, 4-0) face the San Diego Toreros, who are also 4-0 in the Pioneer League, next Saturday.

Lauer gave Drake the lead for good on a 13-yard TD run that made it 9-7 early in the second quarter. Lauer’s second touchdown run extended the lead to 29-17 with 4:22 left in the game. Cross Robinson added nine carries for 44 yards and scored on a 13-yard run that capped the scoring with 2:54 left in the game.

The Eagles (4-4, 2-2) took a 7-0 lead on DeAndre Clayton’s 5-yard run in the first quarter. Mark Pappas’ 16-yard TD pass to Landon Hurst cut the deficit to 22-17 for Morehead State early in the fourth quarter.
Hurst had 11 catches for 123 yards and a score.