CHICAGO (AP) — Matt Holliday hit his sixth career grand slam, powering Michael Wacha and the St. Louis Cardinals past the Chicago White Sox 8-5 on Tuesday night. Holliday homered for the first time since May 12. He returned last Friday after missing 31 games because of a strained right quadriceps. Holliday connected in the fourth inning for his fourth homer. Mark Reynolds added a solo shot in the fifth.

Wacha (11-3) gave up five runs in five innings. Trevor Rosenthal pitched the ninth for his 28th save in 30 chances. Stephen Piscotty, St. Louis’ top hitting prospect, made his major league debut playing left field. He had an infield single in four at-bats and struck out twice. Carlos Rodon (3-3) was tagged for seven hits in four innings as the Cardinals built a 7-0 lead. Chicago lost its third in a row.