KANSAS CITY, Mo. (AP) — Andrew Luck threw for 241 yards and a touchdown, Donald Brown ran 51 yards for another score and the Indianapolis Colts beat the Kansas City Chiefs 23-7 on Sunday in a potential preview of an AFC wild-card playoff game.

The Colts (10-5) took advantage of four turnovers by the Chiefs (11-4) to win for the fifth time in their last six tries against Kansas City. If Indianapolis ends up as the No. 4 seed and the Chiefs the No. 5 for the playoffs, they’ll meet again at Lucas Oil Stadium in two weeks.

Alex Smith threw for 153 yards for Kansas City, but he also lost a fumble and was picked off twice. He had thrown just six interceptions in the first 14 games.

Jamaal Charles ran for 106 yards and the game’s opening touchdown, but Kansas City failed to keep him involved as the Colts scored the final 23 points.